Endometriosis Why is there dysmenorrhea?

         As the growth of endometriosis in the uterine myometrium tissues or organs outside, such as the ovaries, pelvic peritoneum, rectovaginal septum, etc.. As the menstrual cycle in ectopic endometrium is subject to the effects of ovarian hormones thickening, bleeding, but not to stimulate the drainage of surrounding tissue, causing contraction of the uterus, resulting in dysmenorrhea.

         Make the prevention of endometriosis, dysmenorrhea happy to be a free woman

         As the performance of endometriosis because usually hidden strong, it may be found when you have lost the best time of their treatment. To this end, endometriosis from different perspectives for prevention.
         Endometriosis Prevention 1,

Near the menstrual period to avoid unnecessary duplication, or too brutal gynecological pairs of co-diagnosis of endometrial to squeeze into the fallopian tubes so that will be caused by peritoneal seeding.
         Endometriosis Prevention II

Gynecologic surgery to avoid the purposes of close to menstruation must be in operation when the surgery should be gentle to avoid the squeeze force Palace else they might have to squeeze into the fallopian tube lining abdominal cavity.
         Endometriosis Prevention 3,

After the bend over the timely correction of uterine and cervical canal stenosis to blood stasis caused by drainage unobstructed to avoid back.
        Endometriosis Prevention 4,

Cesarean section and cesarean fetal surgery should be taken to avoid uterine contents spilled into the abdominal cavity without rendering the suture when the suture through the uterine incision endometrial layer of abdominal incision suture to prevent endometrial pre-planting application of saline irrigation.

 

         Endometriosis Prevention of five, and strictly control tubal patency test (ventilation-pass liquid), and angiography rules to not just clean the menstrual or directly in the curettage of this cycle so as to avoid the endometrial fragments through the fallopian tubes into the abdominal cavity pressure.

 

         Endometriosis is the growth of endometrium outside the uterine cavity caused by any part of gynecological diseases. Such as ovarian, uterine sacral ligament, the posterior wall of lower uterine segment serosa layer,

Rectum and sigmoid colon lacuna uterine pelvic peritoneum, etc., can also occur in the myometrium, it will be of clinical endometriosis were divided into the external type and internal endometriosis model of endometriosis .

Patients often complained of infertility, dysmenorrhea and pelvic pain treatment. Domestic and foreign reports of patients with endometriosis infertility rate of 40%. The relationship between disease and infertility,

Has been of concern for the clinical view that endometriosis is one of the factors of infertility. Therefore, in clinical practice, on the chief complaint of infertility in women, if the tubal patency, biphasic basal body temperature, endometrial response is good, with normal room after the trial, should consider the possibility of endometriosis.

So what are the reasons for it may lead to female infertility?

1. Ascites quantity, composition and infertility. Of ascites in patients with volume 10-20ml, while the normal <10ml. Ascites in patients with macrophages and lymphocytes increase in ascites acid phosphatase increased,

This activation of macrophage function in the phenomenon, can activate macrophage phagocytosis of sperm affected pregnancy. In addition, macrophages and antigen substances, such as inflammatory material with the back of the blood encounter, it will speed up the breeding division of the sperm and egg cells have a direct toxic effect, thereby interfering with pregnancy.

2. Endometriosis may be associated with non-ovulation.

It is reported that endometriosis, 17% -27% did not ovulate, its mechanisms and LH receptor in patients with follicular cells less relevant.

3. Ovarian luteal phase defect. Was observed that some patients with luteal phase ≤ 10 days and regular pathological examination of endometrial luteal phase defect, its incidence of luteal defects reported 25% -40%. Luteal phase defect not only reduce the pregnancy rate, while increasing the rate of spontaneous abortion.

4. Luteinized follicle did not rupture syndrome (LUF).

Ji Zhi follicle luteinized without ovulation, and luteinizing and follicle stimulating the formation of corpus luteum, but the mature egg is not broken out the corpus luteum and into the abdominal cavity. Although the increase in the concentration of serum progesterone, basal body temperature two-phase, the endometrium was secretory phase change, but laparoscopic ovarian corpus luteum after ovulation did not see the broken hole. Ascites in progesterone levels were significantly lower than the normal.

It is reported that endometriosis in the, LUF the incidence may be as high as 75%, and propose guidelines for testing and progesterone levels in ascites for diagnosis of a better way of this levy.
5. Ascites interleukin â…  and â…¡ increased and infertility. Interleukin-â…  is a kind of macrophage cells to produce specific proteins, can induce T cell differentiation, proliferation, and produce interleukin-â…¡, can stimulate the synthesis of prostaglandins, so that increase in fiber cells, activation and cellular function of immune globulin . Patients with ascites presence of ectopic IL-â…  and IL-â…¡, and with the disease can increase.

6. Ascites prostaglandin (PGF2a) increased secretion and infertility. The study found ascites in patients with prostaglandin concentrations higher than normal. The increased prostaglandin can affect the mature follicles and cause luteal phase defect.

In addition, the ascites increased prostaglandin enable the fallopian tube spasm, rhythmic movement disorder and to make Yunluan Development and decidual changes are not synchronized, and thus affect the Yunluan and implantation.

7. High prolactin hyperlipidemia. It is reported that a group of 14 cases of uterine endometriosis, and 7 patients had breast milk, and 3 cases of increased PRL. Description of infertility endometriosis is often associated with lactation and PRL increased, thereby affecting ovarian function, resulting in no ovulation.

8. Autoimmunity and infertility. Some pairs of endometriosis in serum, cervical secretion antibody was found in patients with serum anti-endometrial and anti-ovarian antibody titers were significantly higher, cervical secretions of the anti-ovarian antibody titers increased.

At the same time, the patient serum and ascites of C3 and C4 complement higher than normal, complement increased mean that the presence of inflammation. This attracted the participation of complement against ectopic endometrial inflammation, is a self-immune response. Anti-ovary antibody rise can affect ovulation and luteal dysfunction, anti-endometrial antibody rise can affect a change to the detriment of endometrial implantation Yunluan.

Thus, infertility in endometriosis due to the formation of a variety of factors, so there must be a stronger strength of the hospital medical treatment