1. Cause a variety of chemical substances and various secretions caused by stimulation.

2. Clinical Features of genital skin, itching, pain, burning sensation. Activities, sexual intercourse, urination, defecation, when heavier. Common local redness, erosion, there are scratches. In severe cases, ulcers or eczema can be formed. Time for the elderly can see that the skin thickening, rough, chapped or lichen-like change.

3. Treatment

(1) for the cause of treatment: attention to hygiene, keeping the vulva clean and dry. Aggressive treatment of diabetes. If urinary fistula, fecal fistula, surgical repair should be as soon as possible.

(2) local treatment: available Bath 1:5000 potassium permanganate solution, or 4% of the boric acid solution, Bath, 2 or 3 times a day. Chinese medicine can also use anti-itch, such as: capillaris, Sophora flavescens, Cnidium, white ringworm skin, soil Fuling and other fried Washed vulva.

Second, bartholinitis

1. Cause in sexual intercourse, childbirth, menstruation and some other cases, the vestibular gland caused by pathogen invasion of vestibular gland inflammation. Common pathogens are: Staphylococcus aureus, Neisseria gonorrhea bacteria, E. coli, Chlamydia trachomatis, Streptococcus, Enterococcus and so on.

2. Clinical features of the typical local red lesions, swelling, heat, pain and dysfunction. Inflammation is first expressed in the duct, followed by the spread of the capsule. Check one or both can be seen below the large labia swelling, tenderness obvious, and sometimes out of pus from the duct mouth.

3. The treatment of acute inflammation should be bed rest, take secretions for culture-sensitive antibiotics. If it has been the formation of abscess, it should be incision and drainage, to relieve symptoms.

Third, Bartholin gland cyst

1. Cause a variety of reasons (infection, secretions thick, scar obstruction) caused by vestibular gland duct openings blocked, the accumulation of glandular secretions and the formation of the cyst cavity.

2. Clinical features conscious there is a cyst vulva, hours may be asymptomatic or have mild bulge and discomfort. Grow up to have sexual intercourse discomfort, Zhuizhang flu. Examination showed the labia majora of the lower 1 / 3 has cystic, oval shape, size, or both may be a single cyst. The surface of non-swelling and tenderness.

3. Treatment of Bartholin’s gland cyst colostomy.

4, vulva condyloma

1. Pathogen characteristics of pathogens, Wei Ren papilloma virus condyloma acuminata (HPV), HPV infection of epithelial cells, mainly, its need for well-differentiated squamous cell replication. Warm, moist skin and mucous membranes at the junction of the vulva beneficial to the growth and reproduction, especially when the sexual life of the site easy to damage, such as the female perineum, posterior vagina. There are many subtypes of HPV,

Condyloma caused by those with HPV6, HPV11-type main, HPV16, HPV18-type times. HPV16, HPV18 type and cervical cancer, the pathogenesis of vulvar cancer.

2. Clinical features

(1) The incubation period of 3 weeks to 8 months, the incidence of 20 to 30-year-old young women mostly, predilection sites were the vulva, the size of the labia, vagina, urethra, cervix, anus around.

(2) Clinical symptoms often not obvious, may have cancer, itching, burning pain. Initially for small sporadic papillary warts, and gradually increased, increased integration between the formation of chicken coronavirus, or cauliflower-like lumps, quality soft surface, wet, pink, dull red or dirty gray, the top may have keratosis or infected ulcer . 12% ~ 34% associated with other types of STI, such as gonorrhea, trichomoniasis, mold, chlamydia infection and even syphilis. About 30% at the same time can be found in the vagina and cervix.

(3) The lesions grow rapidly during pregnancy, after childbirth to reduce or natural healing. During delivery can cause bleeding. The fetus through the birth canal infections, can cause neonatal laryngeal papilloma. Easy to relapse after treatment for recurrent malignant growth should pay attention to the possibility.

3. Diagnosis and differential diagnosis of

(1) diagnosis based on

1) According to the typical clinical features.

2) cytology: light microscope, can be seen characteristic koilocytes.

3) colposcopy: the characteristics of cells and vascular changes.

4) Pathological examination: You can see the characteristic of the hollowing out of cells, immunohistochemical staining detected HPVA9.

5) PCR method to detect HPVDNA.

(2) identification of pseudo-condyloma

1) The pseudo-condyloma patients with multiple asymptomatic or have mild genital itching or Leucorrhea increased, vegetative disorder history.

2) The lesion is located in the medial labia minora symmetric distribution, showing a small flat nipples or villous, with the same mucous membrane color, is often associated with mold, trichomoniasis, or chlamydia infection, with 5% acetic acid after the lesion at acute Tu condyloma white, while the pseudo-condyloma lesions at the same white. Partial performance pregnant women, although the obvious, but subsided after childbirth. Generally no special treatment, there are symptoms can be given to symptomatic treatment.

4. Treatment

(1) drug treatment

1) The local drug treatment: suitable for small lesions, commonly used drugs was 33% ~ 50% trichloroacetic acid, first with 0.5% procaine cotton balls placed in partial moment, post-coated trichloroacetic acid in the lesions, each 1 ~ 2 weeks one time, generally 1 ~ 2 times more than can be cured. Applicator after local edema, white thickening, 2 ~ 3 White off in the future, 7 non-local repair scarring; 5% fluorouracil cream can also be painted locally, mainly for the vulva, perianal, daily l times , 7 ~ 14 days as a course of treatment, the general application of a ~ 2 course of treatment.

2) systemic drug therapy: application of genetic engineering in recent years, interferon (INFα) 100 Wan u, intramuscular injection once every other day for 3 ~ 4 weeks for a course of treatment, but also can be used local injection of basal lesions. Pairs of refractory genital warts and can be used in combination with laser and other treatments.

(2) Cryosurgery: A simple liquid nitrogen or nitric oxide probe frozen tumor and the surrounding l ~ 2mm.

(3) laser treatment: vulvar lesions, the vagina, urethra, cervical lesions are available, less bleeding, does not produce scarring, results were satisfactory.

(4) high-frequency electric knife electrocautery, microwave devices suitable for resection or surgical removal of a giant condyloma acuminata.

(5) The disagreement of treatment during pregnancy, after childbirth may be due to subside, it can not be dealt with. Large lesions affecting the vaginal deliveries, viable cesarean section.